4-HO-MET: High-Purity 4-Hydroxy-MET
4-HO-MET, also known as 4-hydroxy-N-methyl-N-ethyltryptamine or metocin, is a synthetic tryptamine derivative with structural similarity to other hydroxy tryptamines. The compound features a hydroxy substitution at the 4-position of the indole ring and both methyl and ethyl substitutions on the aminoethyl chain.
With a molecular weight of 218.30 g/mol and supplied at a certified purity of ≥98%, 4-ho-met is widely used in advanced laboratory studies. Researchers value this compound for its consistency, well-defined structure, and compatibility with a range of analytical techniques.
Chemistry
| Property | Value |
|---|---|
| CAS Number | 77872-41-4 |
| Molecular Formula | C₁₃H₁₈N₂O |
| Molecular Weight | 218.30 g/mol |
| Purity | ≥98% (HPLC) |
| Synonyms | Metocin, 4-hydroxy-N-methyl-N-ethyltryptamine, 4-ho-met |
| Form | Crystalline solid |
Specifications
| Specification | Details |
|---|---|
| Physical Appearance | Crystalline solid |
| Melting Point | 129–131 °C |
| UV Absorption Maxima | 223, 268, 286, 295 nm |
| Mass Spectrum | MH⁺ peak at 219.0 |
| Storage | Store in a cool, dry, and dark environment |
| Shelf Life | Stable until the stated expiry date when properly stored |
Applications & Uses
4-ho-met is primarily utilized as a standard in analytical chemistry and in receptor binding research. Its structure makes it useful in exploring the relationship between chemical modifications and receptor activity within the serotonin system. It is commonly employed in pharmacological assays, spectroscopy, and chromatography, where high precision and accuracy are critical. Additionally, 4-hydroxy MET provides a valuable reference for laboratories studying structural variations of tryptamine derivatives and their potential effects on receptor interactions.
Safety & Packaging of 4-HO-Met
This compound is packaged in sealed, inert containers that protect it from light and moisture. Each unit is labeled with batch details and expiry information to ensure traceability and reliability. Handling should always be performed using appropriate personal protective equipment including lab coat, gloves, and safety glasses. Work with 4-hydroxy MET in a fume hood to minimize exposure. The product is offered in research-sized quantities, with packaging designed to preserve chemical integrity during transport and storage.
Regulatory
4-HO-MET is sold strictly for scientific research purposes. It is not approved for human or veterinary consumption, clinical use, or any form of therapeutic application. Researchers are responsible for ensuring compliance with all local and international regulations regarding handling and use of research chemicals. Certificates of Analysis and Safety Data Sheets are provided with each batch to support regulatory and quality assurance requirements.




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